3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid
3-Amino-1-Boc-pyrrolidine-3-carboxylic acid
CAS: 862372-66-5
Molecular Formula: C10H18N2O4
3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid - Names and Identifiers
3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C10H18N2O4 |
| Molar Mass | 230.26 |
| Density | 1.243±0.06 g/cm3(Predicted) |
| Boling Point | 365.2±42.0 °C(Predicted) |
| Flash Point | 174.7°C |
| Vapor Presure | 2.5E-06mmHg at 25°C |
| pKa | 2.23±0.20(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.52 |
3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid - Risk and Safety
| Hazard Class | IRRITANT |
3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid - Introduction
The acid is an organic compound whose chemical formula is C11H19NO4.
Nature:
-acrylic is a white to off-white crystalline powder.
-It is stable at room temperature and soluble in organic solvents such as methanol, ethanol and dichloromethane.
Use:
-acid is an organic synthesis intermediate, commonly used in the synthesis of various amino acids and peptides.
-It can be converted into pyrrolidine-3-carboxylic acid (pyrrolidine acid) by the reaction of the deprotecting group (Boc group).
Preparation Method:
There are many methods for preparing acid. A common method is to react 3-amino-1-pyrrolidine-3-carboxylic acid with Boc acid chloride. The specific preparation process is as follows:
-Dissolve 3-amino-1-pyrrolidine-3-carboxylic acid and base (such as triethylamine) in an organic solvent, and add Boc acid chloride;
-Stir the reaction at an appropriate temperature for several hours. After the reaction is complete, filter the mixture;
-Further purify the mixture to obtain acid.
Safety Information:
-must acid is relatively stable under general conditions of use.
-During operation, care should be taken to avoid skin contact and inhalation of its dust.
-Operation should be carried out in a well-ventilated place, and respiratory protection equipment and chemical protective clothing should be used if necessary.
-If ingested, inhaled or in contact with skin, seek medical attention immediately.
Nature:
-acrylic is a white to off-white crystalline powder.
-It is stable at room temperature and soluble in organic solvents such as methanol, ethanol and dichloromethane.
Use:
-acid is an organic synthesis intermediate, commonly used in the synthesis of various amino acids and peptides.
-It can be converted into pyrrolidine-3-carboxylic acid (pyrrolidine acid) by the reaction of the deprotecting group (Boc group).
Preparation Method:
There are many methods for preparing acid. A common method is to react 3-amino-1-pyrrolidine-3-carboxylic acid with Boc acid chloride. The specific preparation process is as follows:
-Dissolve 3-amino-1-pyrrolidine-3-carboxylic acid and base (such as triethylamine) in an organic solvent, and add Boc acid chloride;
-Stir the reaction at an appropriate temperature for several hours. After the reaction is complete, filter the mixture;
-Further purify the mixture to obtain acid.
Safety Information:
-must acid is relatively stable under general conditions of use.
-During operation, care should be taken to avoid skin contact and inhalation of its dust.
-Operation should be carried out in a well-ventilated place, and respiratory protection equipment and chemical protective clothing should be used if necessary.
-If ingested, inhaled or in contact with skin, seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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Product Name: 3-AMINO-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Visit Supplier Webpage Request for quotation
CAS: 862372-66-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 862372-66-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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